Southwest Cheeseburger Casserole



Summer barbecues are one of my favorite things and we pretty much all love a good cheeseburger. But the weather here has been extremely hot and the humidity is, in a word, ridiculous. The idea of standing over a flaming grill isn’t really appealing right now. So, to get the flavors without the heat I made Southwest Cheeseburger Casserole. It’s full of good old American flavors that we all enjoy, without all that standing outside in the 97° heat.

One reason I like this dish is that I can adjust the barbecue sauce to mustard ratio to suit our tastes on any given day. Sometimes my husband can’t handle a lot of mustard but other days he can. But the base flavors are the ones we use in our grilled burgers so it’s a familiar and tasty start. You can play with the sauce and add your own favorite seasonings to the burger mix.

I always use a sweet onion; Vidalia onions if I can get them. And I use K.C. Masterpiece original barbecue sauce. It’s a good, thick sauce so it works well in this recipe. For the biscuits I just get a can of Pillsbury Grands®. The cheese I use varies according to what the family wants. This time it was a fiesta blend. I also use cheddar jack, and sometimes just cheddar.


First I spread the biscuits into the casserole dish. I’ll pinch the seams together and try to make it as even as possible.


I use a lot of cheese! This is 3 cups.


Adding the mustard makes it taste like a real cheeseburger.


The meat mixture goes on top of the biscuits, the sauce on top of the meat, and the cheese tops it all.


The cheese is melted and it’s ready to slice. You can pretty much follow the lines of the biscuits to get 8 pieces.

* This is a great make ahead meal. With just my husband and myself I have dinner one night and have three additional meals. I slice two portions and freeze them together. To reheat I cover the dish with foil so the cheese doesn’t burn and heat at 350 until heated through.

Southwest Cheeseburger Casserole


  • 1 lb. ground round
  • 1 small onion, chopped
  • 1 jalapeño, seeded and diced
  • Salt and pepper to taste
  • 1 1/2 teaspoons garlic powder
  • 1 roll large biscuits (8 count)
  • 1/2 – 3/4 cup thick barbecue sauce
  • 3 tablespoons yellow mustard
  • 2 cups finely shredded cheese


  1. Preheat oven to 350°F
  2. Place ground round in a large skillet over high heat to brown.
  3. Season with salt, pepper, and garlic powder
  4. When meat is nearly cooked through add diced jalapeño.
  5. Cook for about 1 minute then add the onions.
  6. Cook until onions are translucent.
  7. Drain the meat mixture well.
  8. While meat is cooking press the biscuits into an ovenproof casserole, flattening them, and pinching the edges together to form a single layer.
  9. Bake the biscuit until it is set and very light golden brown.
  10. Spread the meat mixture over the biscuit layer.
  11. Mix the barbecue sauce and mustard together until completely blended.
  12. Spread the barbecue mixture over the meat.
  13. Top the sauce with the cheese and bake until the cheese is melted.


Related Posts

Better than Helper Cheeseburger Macaroni

2017-01-31 08:00:04


Bam’s Tuesday Casserole Updated

2017-01-12 08:00:36


Southwest Burger Mac & Cheese

2016-12-12 08:00:16


Swiss Cheeseburgers with Tomato Gravy

2016-11-09 08:00:46


Cheeseburger Skillet

2016-10-26 08:00:17


Cheeseburger Stuffed French Bread

2016-10-14 08:00:13


Farmer's Casserole

2016-09-05 08:00:15


Garden Vegetable Casserole

2016-08-23 08:00:03


Bam's Tuesday Casserole

2016-04-02 13:03:35


Cheesy Chicken, Broccoli & Noodle Casserole

2016-02-28 00:01:29


3 thoughts on “Southwest Cheeseburger Casserole

  • July 29, 2016 at 11:06 am

    This looks amazing and a little dangerous, lol! Pinning and will adding this to my meal plan! Thanks for sharing. ~Blessings~

    • July 29, 2016 at 12:30 pm

      Thank you! I love that I can play with it to change it up a bit. And my husband loves it!

    • July 29, 2016 at 12:41 pm

      Thank you! My husband is crazy about this dish and since I can change it by changing cheese, adding more spice, or making it milder, it always seems new. I hope you enjoy it!


Leave a Reply

Your email address will not be published. Required fields are marked *